Is there a Listeria monocytogenes vaccine?

Listeria monocytogenes (Lm) is a foodborne zoonotic pathogen that causes listeriosis with a mortality rate of 20–30%. Serovar 4b and 1/2b isolates account for most of listeriosis outbreaks, however, no listeriosis vaccine is available for either prophylactic or therapeutic use.

Why is there no vaccine for Listeria?

These results revealed that BMDMs were unsafe vaccine vectors against listeriosis, because they resulted in high cytotoxicity, either containing LM-WT or purified LLO.

What is the treatment for Listeria monocytogenes?

Listeriosis is treated with antibiotics. The most commonly prescribed treatment is intravenous ampicillin. Many physicians also recommend treatment with the antibiotic gentamicin in combination with ampicillin.

How is Listeria administered?

Most normal people spontaneously clear the infection and require no treatment. In contrast, health care professionals should treat people with risk factors quickly with IV antibiotics. Ingesting contaminated food or fluid exposes people to Listeria bacteria.

What type of vaccine is tuberculosis?

The BCG vaccine protects against tuberculosis, which is also known as TB. TB is a serious infection that affects the lungs and sometimes other parts of the body, such as the brain (meningitis), bones, joints and kidneys.

What are the symptoms of Listeria monocytogenes?


  • Fever.
  • Chills.
  • Muscle aches.
  • Nausea.
  • Diarrhea.

Who is at risk for Listeria?

Listeria is most likely to sicken pregnant women and their newborns, adults aged 65 or older, and people with weakened immune systems. Other people can be infected with Listeria, but they rarely become seriously ill.

What antibiotic kills Listeria?

The currently recommended treatment for listeriosis usually consists of a prolonged course of amoxicillin or ampicillin at high doses, often in combination with gentamicin.

How do you prevent Listeria monocytogenes?

How to Reduce Your Risk from Listeria: 3 Easy Steps

  1. Chill at the Right Temperature. The right temperatures slow the growth of Listeria.
  2. Use Ready-to-Eat Foods Quickly! Use ready-to-eat, refrigerated foods by the Use By date on the package.
  3. Keep the Refrigerator Clean. Clean your refrigerator regularly.

Is Listeria a bacteria or virus?

Listeriosis is a serious infection usually caused by eating food contaminated with the bacterium Listeria monocytogenes. An estimated 1,600 people get listeriosis each year, and about 260 die.

What are the steps for prevention of Listeria monocytogenes?