Which statins lower triglycerides the most?
Selected Therapies for Managing Hypertriglyceridemia
| Therapy | Triglyceride reduction (%) | LDL-C increase/reduction (%) |
|---|---|---|
| Statins | 20 to 40 | 18 to 55 reduction |
| Atorvastatin (Lipitor), 10 to 80 mg daily | ||
| Fluvastatin (Lescol), 20 to 80 mg daily at bedtime | ||
| Lovastatin (Mevacor), 10 to 80 mg daily at bedtime |
Which statin has the largest drop in LDL?
Our data indicate that atorvastatin was the most effective statin tested in lowering cholesterol in LDL, non-HDL, and RLP in the fasting and fed states, and getting patients with CHD to established goals, with fluvastatin, pravastatin, lovastatin, and simvastatin having about 33%, 50%, 60%, and 85% of the efficacy of …
What is the controversy surrounding statins?
The controversy in the United Kingdom started in 2013 when the British Medical Journal (BMJ) claimed statins were being overprescribed to people with low risk of heart disease, and that the drugs’ side effects were worse than previously thought.
What is the debate about statins?
The association between use of statins and cognitive dysfunction is controversial, with studies indicating both an increased risk and no increased risk. Most but not all studies show an increased risk of diabetes with statin use. The diabetes risk is more common for high-dose compared with moderate-dose statins.
Which is the best medicine for reducing triglycerides?
Which Medicines Can Lower Triglycerides?
- Fibrates (Fibricor, Lopid, and Tricor)
- Nicotinic acid (Niaspan)
- High doses of omega-3s are needed to lower triglycerides and should be taken only under a doctor’s care. Epanova, Lovaza, and Vascepa are prescription forms of omega-3s.
Which is safer atorvastatin or rosuvastatin?
Atorvastatin was the safest statin as it resulted in the least number of patients at the end of 2 years of treatment with the new onset of microalbuminuria (10.9%) followed by rosuvastatin (14.3%) and then pravastatin (26.6%). Number of patients with no microalbuminuria at baseline but developed it after 2 years.
What is the safest statin on the market?
Simvastatin and pravastatin had the best safety profile, according to this review. Overall, the researchers found a 9 percent increased risk of type 2 diabetes in people taking statins.
What is better atorvastatin or rosuvastatin?
At the end of the titration-to-goal period, rosuvastatin was significantly more effective than atorvastatin on the primary efficacy measure, reducing LDL-C by 52% compared with 46% in the atorvastatin group (p < 0.0001) (table 2).
Do the French take statins?
Nevertheless, seven million French patients take statins, often for longer periods than they do in other countries, at a cost of €2bn a year to the state.