What is the function of the blood-testis barrier?
Thus, the function of the blood-testis barrier is to sequester germ cells residing in the adluminal compartment from the circulatory and lymphatic systems, and together with local immune suppression, to provide an immunoprivileged microenvironment for the completion of meiosis (for reviews, see Refs. 18–21).
What is the blood-testis barrier and what is its major importance to spermatogenesis?
The blood–testis barrier (BTB) that forms from specialized junctions between adjacent Sertoli cells in the seminiferous epithelium is critical for adult fertility, restricting contact between postmitotic germ cells and the immune system and preventing rejection of spermatogenic cells that form after immune tolerance …
What is BTB in spermatogenesis?
The blood-testis barrier (BTB) is found between adjacent Sertoli cells in the testis where it creates a unique microenvironment for the development and maturation of meiotic and postmeiotic germ cells in seminiferous tubes.
What is the blood-testis barrier and why is it important quizlet?
the blood-testis barrier separates the developing sperm from the immune system so the immune system does not attack and destroy the sperms because they a genetically different from the male.
What is the function of the blood-testis barrier Chapter 27?
Tight junctions between these sustentacular cells create the blood–testis barrier, which keeps bloodborne substances from reaching the germ cells and, at the same time, keeps surface antigens on developing germ cells from escaping into the bloodstream and prompting an autoimmune response.
Which cells form the blood-testis barrier quizlet?
Terms in this set (38)
- nurse cells. are found in the seminiferous tubules, form the blood-testis barrier, nourishes the development of sperm, and support/coordinate spermatogenesis.
- blood-testis barrier.
- reproductive system.
- Gametes.
- sperm.
- oocyte.
- fertilization.
- zygote.
What is the purpose of the blood testis barrier quizlet?
What is the function of the blood testis barrier? -Prevents sperm antigens from contacting systemic and lymph circulations, preventing immune response.
What is the function of the blood testis barrier Chapter 27?
Which cells form the blood testis barrier quizlet?
What is the function of the blood testis barrier?
The blood-testis barrier (BTB) is one of the tightest blood-tissue barriers in the mammalian body. It divides the seminiferous epithelium into the basal and the apical (adluminal) compartments.
What is the blood-testis barrier?
The blood–testis barrier is a physical barrier between the blood vessels and the seminiferous tubules of the testes. The term is a bit misleading as it is not a blood-organ barrier, but rather one that is formed by the tight junctions between Sertoli cells of the seminiferous tubules.
What can damage the blood–testes barrier?
The blood–testes barrier can be damaged by trauma to the testes (including torsion or impact), by surgery or as a result of vasectomy.
Do androgens regulate the permeability of the blood-testis barrier?
(2005) Androgens regulate the permeability of the blood-testis barrier. Proc Natl Acad Sci USA102:16696–16700 [PMC free article][PubMed] [Google Scholar]