What is the difference between iron deficiency anemia and pernicious anemia?
Pernicious anemia, also called Biermer’s disease, is less common than iron-deficiency anemia or sickle cell anemia. It’s a type of vitamin B12 anemia because your body doesn’t absorb enough vitamin B12 to make red blood cells. This means there isn’t enough hemoglobin circulating, carrying oxygen throughout your body.
How can we differentiate between various types of anemia?
Your healthcare provider can perform blood tests to tell if you have anemia. The main test is a complete blood count test, also called the CBC. The CBC can tell you how many red blood cells you have, how big they are and what shape they are.
What type of anemia is anemia of chronic disease?
The anemia of chronic disease is a multifactorial anemia. Diagnosis generally requires the presence of a chronic inflammatory condition, such as infection, autoimmune disease, kidney disease, or cancer. It is characterized by a microcytic or normocytic anemia and low reticulocyte count.
Why is iron low in anemia of chronic disease?
The protein hepcidin is the key regulator of anemia of chronic disease. Inflammation leads to increase synthesis of hepcidin. Hepcidin then binds to ferroportin blocking iron export from both liver stores and the GI track.
What is the difference between iron deficiency anemia and folate deficiency anemia?
Anaemia is common; iron deficiency affects health and productivity; folate deficiency in pregnant women causes foetal abnormalities. Few developing countries can measure serum folate or ferritin, but standard automated blood analyses are widely available and can help predict folate and iron deficiency.
What is the difference between pernicious anemia and megaloblastic anemia?
Megaloblastic anemia caused by vitamin B12 deficiency is known as vitamin B12 deficiency anemia. One rare type of vitamin B12 deficiency anemia is pernicious anemia. Pernicious anemia is an autoimmune condition and is due to the lack of a protein in the stomach called intrinsic factor.
What are the 2 types of anemia?
Anemia Types and Causes
- Anemia caused by blood loss.
- Anemia caused by decreased or faulty red blood cell production.
- Anemia caused by destruction of red blood cells.
What are the types of iron deficiency?
Many types of anemia exist, such as iron-deficiency anemia, pernicious anemia, aplastic anemia, and hemo- lytic anemia. The different types of anemia are linked to various diseases and conditions.
What are the symptoms of chronic anemia?
Signs and symptoms, if they do occur, might include:
- Fatigue.
- Weakness.
- Pale or yellowish skin.
- Irregular heartbeats.
- Shortness of breath.
- Dizziness or lightheadedness.
- Chest pain.
- Cold hands and feet.
Which is the chronic disease?
Chronic diseases are defined broadly as conditions that last 1 year or more and require ongoing medical attention or limit activities of daily living or both. Chronic diseases such as heart disease, cancer, and diabetes are the leading causes of death and disability in the United States.
Which laboratory test would be most helpful in differentiating iron deficiency anemia from anemia of chronic disease?
Some experts recommend assessing iron status via serum ferritin or transferrin saturation (Tsat) tests following a finding of low hemoglobin. In patients who are iron deficient, consider evaluation for gastrointestinal malignancy and oral iron supplementation.
Is anemia chronic or acute?
Anemia is classified into acute anemia and chronic anemia. Acute anemia is predominantly due to acute blood loss or acute hemolysis. Chronic anemia is more common and is secondary to multiple causes.