What is sulfur colloid scan?

Technetium Tc 99m sulfur colloid injection is used to find lymph node tumors in patients with breast cancer. It also helps your doctor see an image of your liver, spleen, bone marrow, or a peritoneo-venous (LeVeen) shunt, to see how well they are working.

How is technetium 99m administered?

Depending on site of administration and intended usage, Technetium 99m sulfur colloid enters the capillaries and is transported to the lymph nodes (subcutaneous injection), mixes with peritoneal fluid (intraperitoneal injection), is taken up by reticulocytes (intravenous injection), or enters the gastroesphageal tract …

What is filtered sulfur colloid?

Sulfur Colloid Imaging 99m. Tc-sulfur colloid is a particulate radiopharmaceutical, with particle diameters on the order of 100 to 1000 nm. Following intravenous administration, these particles are rapidly phagocytized by the Kupffer cells of the liver (85%) and the macrophages of the spleen (10%) and bone marrow (5%).

What is the usual particle size of sulfur colloid?

15-100 nm
The ideal particle size for colloids such as filtered (99m)Tc-sulfur colloid ((99m)Tc-FSC) in sentinel node studies is 15-100 nm.

How do you make a sulfur colloid?


  1. Collect components: 10 ml.
  2. Draw up 1 ml.
  3. Draw up 2.5 ml.
  4. Add the 2.5 ml Tc-99m Pertechnetate to the shielded reaction vial.
  5. Immediately add the 1 ml.
  6. Vent vial to release excess vacuum.
  7. Shake gently to mix.

What is sulfur colloid used for?

A substance being studied as a way to find cancer in the body. It is also used to find sentinel lymph nodes in breast cancer. It contains a radioactive substance called technetium linked to a substance called sulfur colloid.

How is technetium 99 prepared?

Technetium -99m is produced by bombarding molybdenum 98Mo with neutrons. The resultant 99Mo decays with a half-life of 66 hours to the metastable state of Tc . This process permits the production of 99mTc for medical purposes.

How is sulphur sol prepared by chemical method?

Sulphur Sol (oxidation): Preparation A Colloidal sol of sulphur can be obtained by passing hydrogen Sulphide into the solution of sulphur dioxide in water or during a solution of an oxidizing agent (Bromine water, nitric acid).

How can colloids be prepared?

However, there are two principal ways of preparation of colloids: Dispersion of large particles or droplets to the colloidal dimensions by milling, spraying, or application of shear (e.g. shaking, mixing, or high shear mixing).

How do you make technetium?

The core of TRIUMF’s new technology to create technetium-99m involves preparing solid targets of molybdenum-100 and then bombarding them with protons generated in a cyclotron, Schaffer said. The team also developed chemistry to isolate and purify the medical isotope.

How is colloidal sulphur prepared?

Surface Chemistry Answer: A colloidal sol of sulphur can be obtained by passing hydrogen sulphide into solution of sulphur dioxide in water or through a solution of an oxidising agent.