What did Stanley Dudrick do?

Stanley J. Dudrick, whose research into hospital nutrition transformed modern surgery, helping save millions of malnourished and critically ill patients who relied on his intravenous feeding technique to eat, died Jan. 18 at his home in Eaton, N.H. He was 84.

Who invented TPN?

Dr. Dudrick
A native of Nanticoke, Pennsylvania, and graduate of Penn’s medical school, Dr. Dudrick was a 32-year-old surgical resident at the Hospital of the University of Pennsylvania when he invented TPN in 1967 alongside preeminent surgeon and then-chair of the Department of Surgery, Jonathan E. Rhoads, GRM’40, HON’60.

Who invented Hyperalimentation?

Stanley Dudrick
Stanley Dudrick is hailed as a medical pioneer. Fifty years ago, he invented a way to feed patients without having to go through their digestive systems. Since then, the technology has saved millions of lives.

What does TPN do to the liver?

Total parenteral nutrition (TPN) can cause a variety of liver diseases, including hepatic steatosis, gallbladder and bile duct damage, and cholestasis. Cholestasis is the most severe complication and can lead to progressive fibrosis and cirrhosis.

How is TPN made?

TPN is made up of two components: amino acid/dextrose solution and a lipid emulsion solution (see Figure 8.9). It is ordered by a physician, in consultation with a dietitian, depending on the patient’s metabolic needs, clinical history, and blood work.

What are the two types of parenteral nutrition?

What are the two types of parenteral nutrition?

  • Partial parenteral nutrition (PPN) is parenteral nutrition given to supplement other kinds of feeding.
  • Total parenteral nutrition (TPN) is complete nutrition delivered intravenously to people who can’t use their digestive systems at all.

How do you calculate TPN?

Total parenteral nutrition calculations

  1. Dextrose% X 50.
  2. Amino Acid% X 100.
  3. All electrolytes combined in mEq/L X 2.
  4. Total = TPN Osmolarity.

Can TPN run with normal saline?

TPN is not compatible with any other type of IV solution or medication and must be administered by itself. TPN must be administered using an EID (IV pump), and requires special IV filter tubing (see Figure 8.10) for the amino acids and lipid emulsion to reduce the risk of particles entering the patient.

Can TPN cause cirrhosis?

Prolonged duration of TPN is marked by bile duct proliferation or ductopenia, portal fibrosis, and expansion of portal triads, and it can progress to cirrhosis and end-stage liver disease.