Who discovered antimalarial drugs?

The discovery of a potent antimalarial treatment by Youyou Tu of China, awarded the Nobel Prize in Medicine, is “one of the greatest examples of the century” of the translation of scientific discovery, according to malaria expert Dyann Wirth of Harvard T.H. Chan School of Public Health.

When was antimalarial drugs discovered?

The antimalarial activity of these compounds was discovered in the 1940s, when they were synthesized and tested as part of an effort to develop a synthetic replacement for quinine. Several drugs in this class, including menoctone, have gone on to human testing, but further development proved unwarranted.

What are the different types of antimalarial drugs?

When several different drugs are recommended for an area, the following table might help in the decision process.

  • Atovaquone/Proguanil (Malarone)
  • Chloroquine.
  • Doxycycline.
  • Mefloquine.
  • Primaquine.
  • Tafenoquine (ArakodaTM)

Which antimalarial drug is best?

Medications. The most common antimalarial drugs include: Chloroquine phosphate. Chloroquine is the preferred treatment for any parasite that is sensitive to the drug.

Who discovered malaria vaccine?

SPf66 is a synthetic peptide based vaccine developed by Manuel Elkin Patarroyo team in Colombia, and was tested extensively in endemic areas in the 1990s.

What is the most common antimalarial drug?

The most common antimalarial drugs include: Chloroquine phosphate. Chloroquine is the preferred treatment for any parasite that is sensitive to the drug. But in many parts of the world, parasites are resistant to chloroquine, and the drug is no longer an effective treatment.

What are the various antimalarial drugs and their mechanism of action?

Mechanism of Action: In Plasmodium falciparum quinine has been found to inhibit nucleic acid synthesis, protein synthesis, and glycolysis; it also binds with hemazoin in parasitized erythrocytes. Quinine is effective as a malarial suppressant and in control of overt clinical attacks.

Which injection is best for malaria?

Severe malaria should be treated with intravenous (IV) antimalarial medications. IV artesunate is the first-line drug for treatment of severe malaria in the United States. Artesunate for InjectionTM is approved by the FDA and is commercially available in the United States.