What is the neurofibromatosis disease?
Neurofibromatoses are a group of genetic disorders that cause tumors to form on nerve tissue. These tumors can develop anywhere in the nervous system, including the brain, spinal cord and nerves. There are three types of neurofibromatosis: neurofibromatosis 1 (NF1), neurofibromatosis 2 (NF2) and schwannomatosis.
Is NF1 a disease or disorder?
Neurofibromatosis 1 (NF1), historically called von Recklinghausen’s disease, is a genetic disorder characterized by increased risk of developing noncancerous (benign) and cancerous (malignant) tumors, as well as various other physical and neurological manifestations.
How does a person get neurofibromatosis?
NF1 is caused by a faulty gene. If the NF1 gene is faulty, it leads to uncontrolled growth (tumours) developing in the nervous system. In half of all cases of NF1, the faulty gene is passed from a parent to their child.
What causes Recklinghausen’s disease?
The cause of VRD is a genetic mutation. Mutations are changes in your genes. The genes make up your DNA, which defines every physical aspect of your body. In VRD, a mutation occurs on the neurofibromin gene, causing an increase in the development of cancerous and noncancerous tumors.
Can NF1 be cured?
There is no known treatment or cure for neurofibromatosis or schwannomatosis. Medication can be prescribed to help with pain. In some cases, growths may be removed surgically or reduced with radiation therapy.
Can neurofibromatosis be cured?
Can NF1 be prevented?
Can neurofibromatosis be prevented or avoided? You cannot avoid NF. You can have genetic testing to see if you carry the gene.
How do I get rid of NF1?
Plastic surgery is usually needed. The surgeon cuts the neurofibromas out of the body before resealing the skin. Depending on the size and location of the neurofibromas, they may be able to be treated with laser surgery or an electric current (electrodessication) instead.
Who is most likely to get neurofibromatosis?
The only true risk factor for developing neurofibromatosis is having a parent who also has the condition. In nearly half of all cases of type 1 and type 2 neurofibromatosis, and in around 15 percent of schwannomatosis cases, the condition is passed down from parent to child.