What is the best medication for restless leg syndrome?

Medications that increase dopamine in the brain. Rotigotine (Neupro) and pramipexole (Mirapex) are approved by the Food and Drug Administration for the treatment of moderate to severe RLS . Short-term side effects of these medications are usually mild and include nausea, lightheadedness and fatigue.

What is the most common drug used for restless leg syndrome?

Dopamine agonists: These are most often the first medicines used to treat RLS. These drugs, including pramipexole (Mirapex), rotigotine (Neupro), and ropinirole (Requip), act like the neurotransmitter dopamine in the brain. Side effects include daytime sleepiness, nausea, and lightheadedness.

Is there an over-the-counter medication for restless legs?

No natural or over-the-counter (OTC) medications consistently improve RLS. OTC sleeping medicines such as Benadryl (an antihistamine) and melatonin may actually worsen symptoms.

What aggravates restless leg syndrome?

In particular, anti-nausea drugs and sedating antihistamines (like Benadryl) block the brain’s dopamine receptors, causing restless legs symptoms. Antidepressants that increase serotonin and antipsychotic medications can also aggravate the condition.

What are the best medications for restless leg syndrome?

Dopamine agonists. RLS is believed to be primarily caused by a shortage of dopamine in the brain.

  • Gabapentinoids. Gabapentinoids were originally developed as anti-seizure (anticonvulsant) medications,but are now widely used to relieve pain.
  • Opioids.
  • Other prescription medications.
  • Symptom relief medications.
  • Supplements.
  • Are there any known drugs to treat restless leg syndrome?

    Unfortunately, there is no known cure for restless legs syndrome. At present, there is no one drug which works for everybody, but most individuals with restless legs syndrome will find some benefit and relief with the currently available medications for treating this disorder, which can be divided into several categories: dopamine-related medications, opiates, benzodiazepines receptor agonists (BRAs), alpha-2 delta medications and iron supplementation.

    What is the home remedy for restless leg syndrome?

    Tonic Water

  • Epsom Salt
  • Camphor
  • Black Strap Molasses
  • Hot&Cold Foot Soaks. The camphor has antispasmodic and therapeutic properties,which help you in relieving inflammation as well as alleviating restless leg syndrome symptoms.
  • What medications cause rest leg syndrome?


  • alcohol,
  • H2-histamine blockers (such as ranitidine[Zantac]and cimetidine[Tagamet]),and certain antidepressants (such as amitriptyline[Elavil,Endep]).