What is Alpha Hydroxymidazolam used for?

α-Hydroxymidazolam a-Hydroxymidazolam is an active, major metabolite in urine and blood of the benzodiazepine, midazolam. Midazolam is sold as Dormicum, Hypnovel, and Versed as a sedative and treatment for insomnia and seizures.

What is Alpha Hydroxymidazolam?

Alpha-hydroxymidazolam is a metabolite of midazolam. Midazolam, marketed in English-speaking countries under the trade names Dormicum, Hypnovel, and Versed, is a short-acting drug in the benzodiazepine class developed by Hoffmann-La Roche in the 1970s.

What is the other name for midazolam?

Midazolam, sold under the brand name Versed, among others, is a benzodiazepine medication used for anesthesia, procedural sedation, trouble sleeping, and severe agitation.

What is the active metabolite of midazolam?

Midazolam converts into its active metabolite alpha-1 hydroxy midazolam, which contributes to 10% of drug action. Midazolam metabolism occurs via hepatic CYP450 enzymes and glucuronide conjugation.

Is nordiazepam the same as diazepam?

The three metabolites of diazepam—nordiazepam, temazepam, and oxazepam—are quickly recognized as individual benzodiazepines, which can be prescribed for a variety of medical conditions.

Is midazolam same as diazepam?

Midazolam is a new imidazobenzodiazepine. It is more potent and has a shorter duration of action than diazepam. Forty patients undergoing upper gastrointestinal endoscopy for the first time were randomized to receive either diazepam or midazolam as the preendoscopic sedative agent.

How strong is midazolam?

The recommended initial IV dose is 0.5mg and should be slowly uptitrated as needed. A dose of 0.025 to 0.05mg/kg administered IM is recommended. In case of concomitant administration of narcotics the midazolam dose should be reduced. The usual dose is 2 to 3mg.

What is nordiazepam generic for?

Nordazepam (INN; marketed under brand names Nordaz, Stilny, Madar, Vegesan, and Calmday; also known as nordiazepam, desoxydemoxepam, and desmethyldiazepam) is a 1,4-benzodiazepine derivative. Like other benzodiazepine derivatives, it has amnesic, anticonvulsant, anxiolytic, muscle relaxant, and sedative properties.

Is nordiazepam active?

It is an active metabolite of diazepam, chlordiazepoxide, clorazepate, prazepam, pinazepam, and medazepam.