What bacteria cause mostly the disease of IgA dominant infection associated glomerulonephritis?
IgA-dominant APIGN is an increasingly recognized morphologic variant of APIGN that typically occurs in association with staphylococcal infection. It is most common in the elderly and in diabetics. Patients typically present with severe renal failure, proteinuria and hematuria.
What is the most common cause of acute glomerulonephritis?
The most common infectious cause of acute GN has historically been infection by Streptococcus species (ie, group A, beta-hemolytic). Two types have been described, involving different serotypes: Serotype 12 – Poststreptococcal nephritis due to an upper respiratory infection, occurring primarily in the winter months.
What causes post infectious glomerulonephritis?
PIGN can be caused by different kinds of germs, including bacteria and viruses. The most common type of PIGN is caused by a type of bacteria called streptococcus (strep). Post-streptococcal glomerulonephritis most often affects children 1-2 weeks after a streptococcal throat infection (“strep throat”).
What are three risk factors for glomerulonephritis?
- A family history of kidney disease.
- Past or current kidney problems.
- Having other health problems such as diabetes and high blood pressure.
- Taking certain medicines.
- Exposure to toxins.
Is IgA nephropathy a glomerulonephritis?
Immunoglobulin A (IgA) is an antibody that plays a key role in your immune system by attacking invading pathogens and fighting infections. But in IgA nephropathy, this antibody collects in the glomeruli, causing inflammation (glomerulonephritis) and gradually affecting their filtering ability.
How is IgA nephropathy treated?
Medications to treat IgA nephropathy include:
- High blood pressure medications. Taking angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) can lower your blood pressure and reduce protein loss.
- Omega-3 fatty acids.
- Statin therapy.
Is glomerulonephritis an infection?
Poststreptococcal GN is a form of glomerulonephritis. It is caused by an infection with a type of streptococcus bacteria. The infection does not occur in the kidneys, but in a different part of the body, such as the skin or throat.
What is the relationship between group A streptococcal infection and glomerulonephritis?
Post-streptococcal glomerulonephritis (PSGN) is an immunologically-mediated sequela of pharyngitis or skin infections caused by nephritogenic strains of Streptococcus pyogenes. S. pyogenes are also called group A Streptococcus or group A strep.
What are the different types of glomerulonephritis?
- 2.1 Minimal change disease.
- 2.2 Focal segmental glomerulosclerosis.
- 2.3 Membranous glomerulonephritis.
- 2.4 Thin basement membrane disease.
- 2.5 Fibronectin glomerulopathy.