Researchers have developed new migraine drugs which seem very promising in cutting down the frequency of migraine attacks, according to reports. Two medicines have been developed which are long-acting and can be administered as shots every month, depending on the frequency of the painful headaches.
Reports state that these newly-developed drugs are the first of their kinds of preventive medicines which have been specifically developed for treating migraine. The drugs work by interfering with a substance involved in modifying nerve signaling and progression of pain and symptoms.
Commenting on the new drugs, neurology chief at Cincinnati Children’s Hospital Medical Center, Dr. Andrew Hershey said that the drugs will provide a “whole new direction” for the treatment of the condition and are an important advance for people who don’t want to take or aren’t helped by the daily pills sometimes used now to prevent recurrences of the episodes, according to CBS News.
Dr. Hershey had no role role in the research, however he has tested other migraine drugs and written about them.
Over a billion people across the world are affected by migraine, including more than 38 million people in the United States alone. Migraines are severe headaches which have a disabling effect on the patient and can often cause vision problems, sensitivity to light, noise or smells, and nausea. These excruciating headaches can often render people unable to perform simple tasks or even hold a conversation.
One of the studies of the drugs tested erenumab, from Amgen and Novartis, in nearly 900 people who had eight to nine migraine attacks per month on ab average. Reports state that almost half of these patients had already tried other preventive medicines to treat their migraine.
They were then given a high dose of the drug for a period of six months, and the researchers noted a significant improvement in their condition.
The findings of the study were published in the New England Journal of Medicine on Wednesday.